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Registro Completo |
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Biblioteca(s): |
Embrapa Pecuária Sudeste. |
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Data corrente: |
15/01/2024 |
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Data da última atualização: |
15/01/2024 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
ANHOLETO, L. A.; BLANCHARD, S.; WANG, H. V.; CHAGAS, A. C. de S.; HILLER, N. K.; FARAONE, N. |
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Afiliação: |
LUÍS ADRIANO ANHOLETO, Acadia University; SOPHIA BLANCHARD, Acadia University; HAOZHE VINCENT WANG, Acadia University; ANA CAROLINA DE SOUZA CHAGAS, CPPSE; NEIL KIRK HILLIER, Acadia University; NICOLETTA FARAONE, Acadia University. |
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Título: |
In vitro acaricidal activity of essential oils and their binary mixtures against ixodes scapularis (Acari: Ixodidae). |
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Ano de publicação: |
2024 |
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Fonte/Imprenta: |
Ticks and Tick-borne Diseases, v. 15, n. 2, mar. 2024, 102309. |
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DOI: |
10.1016/j.ttbdis.2024.102309 |
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Idioma: |
Inglês |
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Conteúdo: |
Ixodes scapularis ticks are vectors of infectious agents that cause illness in humans, including Lyme disease. Recent years have seen a surge in tick-borne diseases (TBD) resulting in a high demand for tick management products. Plants offer a valuable source of active compounds for the development of novel, eco-friendly tick control products, reducing potential risks to human and animal health. Essential oils (EOs) have emerged as potential acaricides and repellents against ticks providing an alternative to synthetic chemicals and aiding in the prevention of TBD by lowering the risk of tick bites. We investigated the acaricidal activity of EOs from lemongrass (Cymbopogon citratus), geranium (Pelargonium x asperum), savory thyme (Thymus saturejoides), and white thyme (Thymus zygis) on I. scapularis. The interactions (i.e., synergistic, antagonistic, or additive) of their binary mixtures were also evaluated. EO samples were analyzed via gas chromatography-mass spectrometry to determine their chemical composition. The adult immersion test was used to determine the lethal concentration (LC50) of each EO alone and in mixtures. Quantitative assessment of synergistic, additive, or antagonistic effect of the binary mixtures was performed by calculating the combination index. Strong acaricidal activity was recorded for savory thyme and white thyme EOs, with LC50 values of 28.0 and 11.0 μg/μL, respectively. The LC50 of lemongrass and geranium EOs were 49.0 and 39.7 μg/μL, respectively. Among the tested EOs, savory thyme and white thyme had a strong acaricidal effect on I. scapularis, which might be linked to the presence of carvacrol (26.05 % ± 0.38) and thymol (53.6 % ± 2.31), main components present in savory thyme and white thyme EOs, respectively. The tick killing efficacy of lemongrass and geranium EOs was lower when mixed than when used separately (LC50 of 65.3 µg/µL). The same happened with savory thyme and white thyme EOs, except at 9.75 µg/µL where they had a synergistic effect (LC50 of 58.3 µg/µL). Lemongrass and savory thyme EOs had a synergistic effect at low concentrations, and an antagonistic effect at higher concentrations (LC50 of 95.4 µg/µL). Lemongrass and white thyme EOs had a synergistic effect against ticks from 15 to 120 µg/µL (LC50 of 18.5 µg/µL) similar to white thyme EO. Geranium and savory thyme EOs had an antagonistic effect at all concentrations, with an LC50 of 66.8 µg/µL. Geranium and white thyme EOs also had an antagonistic effect, except at 12.7 µg/µL where they had a synergistic effect (LC50 of 66.8 µg/µL). The interaction observed when combining selected essential oils suggests promising potential for developing acaricidal formulations aimed at controlling ticks and curbing the transmission of tick-borne disease agents. MenosIxodes scapularis ticks are vectors of infectious agents that cause illness in humans, including Lyme disease. Recent years have seen a surge in tick-borne diseases (TBD) resulting in a high demand for tick management products. Plants offer a valuable source of active compounds for the development of novel, eco-friendly tick control products, reducing potential risks to human and animal health. Essential oils (EOs) have emerged as potential acaricides and repellents against ticks providing an alternative to synthetic chemicals and aiding in the prevention of TBD by lowering the risk of tick bites. We investigated the acaricidal activity of EOs from lemongrass (Cymbopogon citratus), geranium (Pelargonium x asperum), savory thyme (Thymus saturejoides), and white thyme (Thymus zygis) on I. scapularis. The interactions (i.e., synergistic, antagonistic, or additive) of their binary mixtures were also evaluated. EO samples were analyzed via gas chromatography-mass spectrometry to determine their chemical composition. The adult immersion test was used to determine the lethal concentration (LC50) of each EO alone and in mixtures. Quantitative assessment of synergistic, additive, or antagonistic effect of the binary mixtures was performed by calculating the combination index. Strong acaricidal activity was recorded for savory thyme and white thyme EOs, with LC50 values of 28.0 and 11.0 μg/μL, respectively. The LC50 of lemongrass and geranium EOs were 49.0 and 39.7 μg/μL, respectively... Mostrar Tudo |
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Thesaurus Nal: |
Carvacrol; Ixodes scapularis; Terpenoids; Thymol. |
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Categoria do assunto: |
H Saúde e Patologia |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/1160802/1/InVitroAcaricidalActivity.pdf
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Marc: |
LEADER 03557naa a2200241 a 4500
001 2160802
005 2024-01-15
008 2024 bl uuuu u00u1 u #d
024 7 $a10.1016/j.ttbdis.2024.102309$2DOI
100 1 $aANHOLETO, L. A.
245 $aIn vitro acaricidal activity of essential oils and their binary mixtures against ixodes scapularis (Acari$bIxodidae).$h[electronic resource]
260 $c2024
520 $aIxodes scapularis ticks are vectors of infectious agents that cause illness in humans, including Lyme disease. Recent years have seen a surge in tick-borne diseases (TBD) resulting in a high demand for tick management products. Plants offer a valuable source of active compounds for the development of novel, eco-friendly tick control products, reducing potential risks to human and animal health. Essential oils (EOs) have emerged as potential acaricides and repellents against ticks providing an alternative to synthetic chemicals and aiding in the prevention of TBD by lowering the risk of tick bites. We investigated the acaricidal activity of EOs from lemongrass (Cymbopogon citratus), geranium (Pelargonium x asperum), savory thyme (Thymus saturejoides), and white thyme (Thymus zygis) on I. scapularis. The interactions (i.e., synergistic, antagonistic, or additive) of their binary mixtures were also evaluated. EO samples were analyzed via gas chromatography-mass spectrometry to determine their chemical composition. The adult immersion test was used to determine the lethal concentration (LC50) of each EO alone and in mixtures. Quantitative assessment of synergistic, additive, or antagonistic effect of the binary mixtures was performed by calculating the combination index. Strong acaricidal activity was recorded for savory thyme and white thyme EOs, with LC50 values of 28.0 and 11.0 μg/μL, respectively. The LC50 of lemongrass and geranium EOs were 49.0 and 39.7 μg/μL, respectively. Among the tested EOs, savory thyme and white thyme had a strong acaricidal effect on I. scapularis, which might be linked to the presence of carvacrol (26.05 % ± 0.38) and thymol (53.6 % ± 2.31), main components present in savory thyme and white thyme EOs, respectively. The tick killing efficacy of lemongrass and geranium EOs was lower when mixed than when used separately (LC50 of 65.3 µg/µL). The same happened with savory thyme and white thyme EOs, except at 9.75 µg/µL where they had a synergistic effect (LC50 of 58.3 µg/µL). Lemongrass and savory thyme EOs had a synergistic effect at low concentrations, and an antagonistic effect at higher concentrations (LC50 of 95.4 µg/µL). Lemongrass and white thyme EOs had a synergistic effect against ticks from 15 to 120 µg/µL (LC50 of 18.5 µg/µL) similar to white thyme EO. Geranium and savory thyme EOs had an antagonistic effect at all concentrations, with an LC50 of 66.8 µg/µL. Geranium and white thyme EOs also had an antagonistic effect, except at 12.7 µg/µL where they had a synergistic effect (LC50 of 66.8 µg/µL). The interaction observed when combining selected essential oils suggests promising potential for developing acaricidal formulations aimed at controlling ticks and curbing the transmission of tick-borne disease agents.
650 $aCarvacrol
650 $aIxodes scapularis
650 $aTerpenoids
650 $aThymol
700 1 $aBLANCHARD, S.
700 1 $aWANG, H. V.
700 1 $aCHAGAS, A. C. de S.
700 1 $aHILLER, N. K.
700 1 $aFARAONE, N.
773 $tTicks and Tick-borne Diseases$gv. 15, n. 2, mar. 2024, 102309.
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Embrapa Pecuária Sudeste (CPPSE) |
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| 1. |  | Silva-Filho, E. V.; Kütter, V. T.; Figueiredo, T. S.; Tessier, E.; Rezende, C. E.; Teixeira, D. C.; SILVA, C. A. da; Donard, O. F. X. Mercury speciation in plankton from the Cabo Frio Bay, SE - Brazil. Environ Monit Assess, 14, August, 2014.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Tabuleiros Costeiros. |
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| 2. | | SILVA, C. A. da; TESSIER, E.; KUTTER, V. T.; WASSERMAN, J. C.; DONARD, O. F. X.; SILVA FILHO, E. V. Mercury speciation in fish of the Cabo Frio upwelling region, SE-Brasil. Brazilian Journal of Oceanography, São Paulo, v. 59, n. 3, p. 259-266, 2011.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
| Biblioteca(s): Embrapa Tabuleiros Costeiros. |
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| 3. | | SILVA, C. A. da; TESSIER, E.; SIVA FILHO, E. V.; WASSERMAN, J. C. F. A. Biomagnificación del mercurio en la cadena pelágica marina de la región de surgencia de Cabo Frío, RJ, Brasil. In: SIMPOSIO INTERNACIONAL DE CIENCIAS DEL MAR, 2., 2009, Vigo. Resúmenes... Vigo: Faculdade de Ciencias del Mar, 2009.| Tipo: Resumo em Anais de Congresso |
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